The authors said cases were consistent with seasonal fluctuations and redistribution of cases during the pandemic, but that epidemiologic monitoring continues.Ī post hoc analysis of a phase 3 randomized, controlled trial estimates that two doses of the Novavax (NVX-CoV2373) COVID-19 vaccine were 100% effective against hospitalization by 95 days during a period dominated by the SARS-CoV-2 Alpha variant.įor the analysis, published late last week in Vaccine, Novavax researchers parsed data from the PREVENT-19 trial of two doses of the Novavax vaccine or a placebo given 21 days apart to 25,482 patients in the United States and Mexico. Investigators said more research is needed to identify risk factors and causes of the rare conditions.Įxperts told CNN that possible explanations could be less exposure to pathogens during the earlier phases of the pandemic or a higher disease burden in the past year, now that COVID-19 cases have fallen.Ī September 2022 report in Morbidity and Mortality Weekly Report examined a possible increase in pediatric streptococcal brain abscesses and epidural empyemas, finding a decline at the start of the pandemic, with an increase in the summer of 2021 and a peak in March 2022. Three had ear infections, and one patient had a sinus infection. Nine patients had experienced cold symptoms, and none had been diagnosed as having COVID-19. Streptococcus intermedius was the most common bacterial pathogen.
The median age was 12, and 14 of the patients were boys. However, 18 cases were reported in 2022, none of them fatal. The investigation by EIS officials found that, from 2015 to 2021, Clark County averaged about four such cases a year. In the Nevada cluster, health officials in October received reports of a higher-than-expected number of kids who had intracranial abscesses. The Centers for Disease Control and Prevention (CDC) continues to investigate increased reports of brain abscesses in children, which includes a 2022 cluster from Nevada's Clark County that was detailed last week at the CDC Epidemic Intelligence Service (EIS) annual meeting in Atlanta.ĭoctors in other locations are seeing similar cases, according to CNN.
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